General instructions for Urine porphyrins

Analysis that measures the levels of porphyrins in the urine, used to diagnose disorders known as porphyrias.

  • Definition: An analysis that measures porphyrin levels in the urine, used to diagnose disorders known as porphyrias.
  • Fasting: No fasting is necessary for this test. You can eat normally and it is recommended that you maintain your usual intake of liquids and water throughout the time the collection lasts.
  • Medication: Certain drugs (such as some sedatives, antibiotics, or oral contraceptives) can significantly alter porphyrin levels. Nonetheless, the decision to stop, maintain, or adjust your usual medication must always be discussed with your doctor.
  • Clothing and Accessories: As it is a collection you will carry out at your own home, there are no specific clothing requirements nor any restriction regarding the use of jewelry, piercings, or metal objects.
  • Specific Requirements: Generally, it is a 24-hour urine collection. It is vital to protect the sample from light, as porphyrins are destroyed when exposed to sunlight or artificial light. The lab will provide an opaque (amber-colored) container; if it is transparent, you should wrap it completely in aluminum foil. Furthermore, you must keep the container in the refrigerator during the 24 hours the collection lasts and totally abstain from consuming alcohol in the preceding days and during the test.
  • Expected discomfort or pain from the test: None. It is a completely painless and non-invasive test, as it only involves urinating naturally into a container provided for it.